Talling Guide

Linked media - Associated media “This reconceptualization that we’re proposing affects not a small minority of people,” said Dr. Juan Fortea, an author of the study and the director of the Sant Pau Memory Unit in Barcelona, Spain. “Sometimes we say that we don’t know the cause of Alzheimer’s disease,” but, he said, this would mean that about 15 to 20 percent of cases “can be tracked back to a cause, and the cause is in the genes.” The idea involves a gene variant called APOE4. Scientists have long known that inheriting one copy of the variant increases the risk of developing Alzheimer’s, and that people with two copies, inherited from each parent, have vastly increased risk. The new study, published in the journal Nature Medicine, analyzed data from over 500 people with two copies of...

Related media - Connected media As he lay on his deathbed, his publisher gave him a gift of 12 bottles of wine. By then Beethoven knew he could never drink them. He whispered his last recorded words: “Pity, pity — too late!” For a composer, deafness had been perhaps the worst affliction. At age 30, 26 years before his death, Beethoven wrote: “For almost 2 years I have ceased to attend any social functions, just because I find it impossible to say to people: I am deaf. If I had any other profession, I might be able to cope with my infirmity, but in my profession it is a terrible handicap. And if my enemies, of whom I have a fair number, were to hear about it, what would they say?” When he was 32, Beethoven mourned that he could not hear a flute, or a shepherd singing, which, he wrote,...

Connected media - Linked media Mr. Bouton said that he had not been aware of the full extent of Dr. Oxnam’s alcoholism and that he had had inklings about his behavioral problems. He said that it was remarkable that Dr. Oxnam had been able to work through them. But in 1992, Dr. Oxnam told the society’s board that he was going to resign. “The Bob part of me was touched that they pressured me to reconsider,” he wrote in his book. But he left. In addition to his wife, whom he married in 1993 and who was president of the Asia Society from 2004 to 2012, his survivors include his daughter, Deborah Betsch, and his son, Geoff Oxnam, both from his marriage to Barbara Foehl, which ended in divorce in 1993, and four grandchildren. After leaving the Asia Society, Dr. Oxnam hosted and wrote a seri...

Linked media - Related media The loss of biodiversity played an especially large role in driving up disease risk, the researchers found. Many scientists have posited that biodiversity can protect against disease through a phenomenon known as the dilution effect. The theory holds that parasites and pathogens, which rely on having abundant hosts in order to survive, will evolve to favor species that are common, rather than those that are rare, Dr. Rohr said. And as biodiversity declines, rare species tend to disappear first. “That means that the species that remain are the competent ones, the ones that are really good at transmitting disease,” he said. Lyme disease is one oft-cited example. White-footed mice, which are the primary reservoir for the disease, have become more dominant on...